Abstract: Hydrogen energy, as a green and clean energy, has received widespread attention in the field of new energy vehicles. In particular, cryogenic liquid hydrogen has the advantage of high hydrogen storage density, making it an ideal hydrogen storage method for vehicles. The liquid hydrogen tank is one of the key components of a liquid hydrogen vehicle and its support structure can directly affect its adiabatic and mechanical properties. In this paper, the liquid hydrogen tanks based on the six-point support scheme and the eight-point support scheme are compared regarding intensity check, modal analysis, and random vibration fatigue analysis through the finite element analysis method. The results show that when the radial thickness of the glass fibre reinforced plastic column is 10 mm, the eight-point support scheme can meet the intensity standards, but the six-point support scheme cannot meet the intensity requirements. To meet the intensity control conditions, the liquid hydrogen tank in the six-point support scheme requires an increase in the radial thickness of the glass fibre reinforced plastic columns, but it also results in a larger support heat leakage. Under the current design, the support heat loss of the liquid hydrogen tank in the six-point support scheme and the eight-point support scheme are 23.65 W and 22.49 W, respectively, and the fatigue life is 1.01×10⁷ times and 9.19×10⁷ times, respectively. Compared with the eight-point support scheme, although the number of support ends is reduced in the six-point support scheme, the adiabatic performance is not effectively improved, and the service life of the liquid hydrogen tank is significantly reduced. The current research results provide a scientific and reliable theoretical basis for the engineering design of the support structure of on-board liquid hydrogen tanks, and at the same time play an important role in improving the safety and stability of the structure in practical engineering applications. These research advances are expected to further promote the innovation and development of on-board liquid hydrogen storage and transport technology.