Abstract: Quartz-flexibility-accelerometer,with high precision,can be used as sensitive acceleration to monitor microvibration of spacecraft on-orbit. This paper introduced the analysis result of influencing the accelerometer in the low pressure environment. It also illustrated the mechanism analysis and experiment results. The results showed that the effect to the scale factor was less than 0.1%, which had very little influence on the measurement accuracy and can be ignored. Through noise tests in the cave laboratory,this experiment tested and compared the noise of the quartz pendulum between one bar air pressure and 3.9 Pa air pressure environment. This result showed that the air pressure environment had very delicate influence on the measure precision of the accelerometer. The analysis result of the low pressure environment can provide some references to the long-term on-orbit application of quartz-flexibility-accelerometer.