Abstract: The refrigeration devices to calibration experiment of hard X-ray modulation telescope are researched, it include the refrigeration device of low energy (LE) detector and the refrigeration devices of medium energy (ME) detector. The devices are consistent in structure and both cooled by liquid nitrogen, they are formed by liquid nitrogen tank, heat conductivity column, uniform temperature plate, radiation screen, and so on. The temperature of liquid nitrogen tank is controlled by adjusting the flow of liquid nitrogen and heating rod, the temperature of uniform temperature plate is controlled by adjusting the diameter of insulated pole and heating film. Due to the big volume of device, the key technical difficulty is that ensure the temperature of uniform temperature plate could be controlled in a big range and good temperature uniformity on the premise that fast enough cooling speed. This paper introduces the structure of refrigeration devices, the numerical simulation results on thermal analysis by Ansys Workbench and the experimental test results. The experimental results show that some difference between the numerical simulation and experimental test. The temperature difference of liquid nitrogen tank and the contact resistance have a big effect on the temperature uniformity of uniform temperature plate. Through adjusting the heat conductivity column, the contact resistance and the heating rod of liquid nitrogen tank, the temperature of two uniform temperature plates could be controlled from 193K to 273K, the temperature control stability better than ± 0.1K and the temperature uniformity better than 1. 96K.