Abstract: With the advantages of small size,light weight,high reliability,quick start and the cold end without moving part,miniature JT cryocooler is wildly applied in infrared seeker. Gas consumption is different for different types of JT cooler. The volume,weight,working time of an infrared seeker bottle is determined by a JT cryocooler's gas consumption. We have done some experimental research on Gas consumption about four kinds of Joule-Thomson Cooler in different condition. Some advices are supplied for different engineering applications by the research.