Abstract: As the instruments and equipments of microelectronic systems,aerospace and military field highly integrated,it is significant to solve the problem of disserting heat efficiently under high heat flux.Micro/mini-channel boiling heat transfer device with its characteristics such as small volume,light weight,large heat release has been paid more and more attention.However,the mechanism of heat and mass transfer in micro/mini-channels has not been thoroughly studied.This paper introduces the latest progress of the two phase flow in micro/mini-channels.We reviewed and analyzed the two phase flow models,refrigerants and the impact of channel configurations.