Abstract: Plate heat exchanger,which is widely used in industrial,is used as the research object to simulate flow of fluid channel and heat transfer of hot and cold dual-channel consisted of the herringbone corrugated plates,and analyze the velocity field,temperature field and pressure field of plate heat exchanger's flow passage,study the influence law of the corrugated board sheet's geometric parameters on heat transfer characteristics.Dissipation generated in the heat transfer process is used as the objective function to optimize the corrugated board sheet's structure parameters which used sequential quadratic programming(NLPQL).Heat transfer performance after optimization of the heat exchanger has improved significantly.