Abstract: In this paper,the research,application and development of temperature cooling and heating control system of in space environment simulator are summarized.Various cooling processes using liquid nitrogen,liquid helium,helium expansion refrigeration system,cryogenic gas cryocooler and steam compression cycle refrigeration are classified and their principles are expounded in detail,their advantages and disadvantages are compared.Some opinions and suggestions are put forward on the design,application suitability and economy of various cooling and heating control processes,especially the open liquid nitrogen process,gravity liquid supply process,liquid nitrogen vacuum evaporation process and heat regen-erative gas nitrogen cooling and heating process.